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A chronic skeletal disorder characterized by abnormal and excessive bone remodeling. In this condition, the body's process of breaking down old bone and replacing it with new bone is disrupted, leading to the formation of bone that is larger, weaker, and more fragile than normal.
Common symptoms
Bone pain (the most common symptom)
Joint pain and stiffness
Bone deformities, such as bowing of the legs
Hearing loss or headaches (if the skull is affected)
Numbness, tingling, or weakness in limbs due to nerve compression
Increased head size
Skin feeling warm over the affected bone
Possible causes
Overactive osteoclasts (cells that break down bone) causing rapid bone resorption
Overactive osteoblasts (cells that form bone) creating weak, disorganized new bone
Genetic mutations or family history of the disorder
Suspected environmental triggers, such as slow-acting viral infections
Medical treatment
Bisphosphonates (e.g., zoledronic acid, pamidronate) to regulate bone turnover
Nonsteroidal anti-inflammatory drugs (NSAIDs) for pain relief
Calcitonin injections (in specific cases)
Supportive therapies including physiotherapy and occupational therapy
Assistive devices like walking sticks or shoe inserts
Surgery for complications such as fractures, severe arthritis, or nerve decompression
Ayurvedic perspective
In Ayurveda, Paget's disease is primarily correlated with Asthi Dhatu Kshaya (depletion or degeneration of bone tissue) and Asthi Vikriti (bone deformity). It is viewed as a metabolic disorder of the Asthivaha Srotas (bone-carrying channels) where an imbalance in Asthi Dhatvagni (bone-specific metabolic fire) leads to the disorganized and rapid production of poor-quality bone. This process is driven by the vitiation of Vata Dosha, which governs the structural integrity and catabolic processes of the skeletal system.
Ayurvedic dietary guidelines
Include 'Snigdha' (unctuous) foods like Cow Ghee and Sesame oil to lubricate and pacify Vata
Consume calcium and mineral-rich foods such as Ragi (finger millet), black sesame seeds, and almonds
Drink warm A2 cow's milk medicated with turmeric or ashwagandha
Favor sweet, sour, and salty tastes while strictly avoiding dry (Ruksha) and cold foods
Include green leafy vegetables and seasonal fruits to support Dhatvagni
